Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria

[Image: see text] Milk is an attractive lipid-based formulation for the delivery of poorly water-soluble drugs to pediatric populations. We recently observed that solubilization of artefenomel (OZ439) during in vitro intestinal lipolysis was driven by digestion of triglycerides in full-cream bovine...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Pharm
Egile Nagusiak: Salim, Malinda, Khan, Jamal, Ramirez, Gisela, Murshed, Mubtasim, Clulow, Andrew J., Hawley, Adrian, Ramachandruni, Hanu, Beilles, Stephane, Boyd, Ben J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2019
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448114/
https://ncbi.nlm.nih.gov/pubmed/30830789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.8b01333
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