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Rab1A promotes proliferation and migration abilities via regulation of the HER2/AKT-independent mTOR/S6K1 pathway in colorectal cancer

Colorectal carcinoma (CRC) is one of the most common malignancies worldwide and the second leading cause of cancer-related deaths in the US. Recently, Rab1A has been reported to be an activator of mTORC1 and p-S6K1, which is downstream of mTORC1. However, the association between Rab1A and p-S6K1 in...

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Библиографические подробности
Опубликовано в: :Oncol Rep
Главные авторы: Cheng, Zhengwu, Shao, Xinyu, Xu, Menglin, Wang, Junfeng, Kuai, Xiaoyi, Zhang, Liping, Wu, Jian, Zhou, Chunli, Mao, Jiading
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448090/
https://ncbi.nlm.nih.gov/pubmed/30896866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2019.7071
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