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JARID1B expression and its function in DNA damage repair are tightly regulated by miRNAs in breast cancer

JARID1B/KDM5B histone demethylase's mRNA is markedly overexpressed in breast cancer tissues and cell lines and the protein has been shown to have a prominent role in cancer cell proliferation and DNA repair. However, the mechanism of its post‐transcriptional regulation in cancer cells remains e...

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Podrobná bibliografie
Vydáno v:Cancer Sci
Hlavní autoři: Mocavini, Ivano, Pippa, Simone, Licursi, Valerio, Paci, Paola, Trisciuoglio, Daniela, Mannironi, Cecilia, Presutti, Carlo, Negri, Rodolfo
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447846/
https://ncbi.nlm.nih.gov/pubmed/30588710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13925
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