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Frizzled 2‐induced epithelial‐mesenchymal transition correlates with vasculogenic mimicry, stemness, and Hippo signaling in hepatocellular carcinoma

Prior observation has indicated that Frizzled 2 (FZD2)‐induced epithelial‐mesenchymal transition (EMT) could be a key step in metastasis and early recurrence of hepatocellular carcinoma (HCC). However, the mechanism underlying tumor development and progression due to aberrant FZD2 expression is poor...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Ou, Huohui, Chen, Zhanjun, Xiang, Leyang, Fang, Yinghao, Xu, Yuyan, Liu, Qin, Hu, Zhigang, Li, Xianghong, Huang, Yu, Yang, Dinghua
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447835/
https://ncbi.nlm.nih.gov/pubmed/30677195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13949
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