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Assessment of corneal substrate biomechanics and its effect on epithelial stem cell maintenance and differentiation

Whilst demonstrated extensively in vitro, the control of cell behaviour via modulation of substrate compliance in live tissues has not been accomplished to date. Here we propose that stem cells can be regulated solely through in situ modulation of tissue biomechanics. By first establishing, via high...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gouveia, Ricardo M., Lepert, Guillaume, Gupta, Suneel, Mohan, Rajiv R., Paterson, Carl, Connon, Che J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447573/
https://ncbi.nlm.nih.gov/pubmed/30944320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09331-6
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