Gene-by-sex interactions in mitochondrial functions and cardio-metabolic traits

We studied sex differences in over 50 cardio-metabolic traits in a panel of 100 diverse inbred strains of mice. The results clearly showed that the effects of sex on both clinical phenotypes and gene expression depend on the genetic background. In support of this, genetic loci associated with the tr...

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Pubblicato in:Cell Metab
Autori principali: Norheim, Frode, Hasin-Brumshtein, Yehudit, Vergnes, Laurent, Krishnan, Karthickeyan Chella, Pan, Calvin, Seldin, Marcus M., Hui, Simon T., Mehrabian, Margarete, Zhou, Zhiqiang, Gupta, Sonul, Parks, Brian W., Walch, Axel, Reue, Karen, Hofmann, Susanna M., Arnold, Arthur P., Lusis, Aldons J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447452/
https://ncbi.nlm.nih.gov/pubmed/30639359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.12.013
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