Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr (-/-) mice

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, particularly in obese and type 2 diabetic individuals. NAFLD ranges in severity from benign steatosis to nonalcoholic steatohepatitis (NASH); and NASH can progress to cirrhosis, primary hepatocel...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Garcia-Jaramillo, Manuel, Spooner, Melinda H., Löhr, Christiane V., Wong, Carmen P., Zhang, Weijian, Jump, Donald B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447358/
https://ncbi.nlm.nih.gov/pubmed/30943218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214387
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