A trivalent gC2/gD2/gE2 vaccine for herpes simplex virus generates antibody responses that block immune evasion domains on gC2 better than natural infection

Vaccines for prevention and treatment of genital herpes are high public health priorities. Our approach towards vaccine development is to focus on blocking virus entry mediated by herpes simplex virus type 2 (HSV-2) glycoprotein D (gD2) and to prevent the virus from evading complement and antibody a...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Hook, Lauren M, Awasthi, Sita, Dubin, Jonathan, Flechtner, Jessica, Long, Deborah, Friedman, Harvey M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447314/
https://ncbi.nlm.nih.gov/pubmed/30551986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.11.076
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