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A novel BAP1 mutation is associated with melanocytic neoplasms and thyroid cancer

Germline mutations in the tumor suppressor gene, BRCA-1 associated protein (BAP1), underlie a tumor predisposition syndrome characterized by increased risk for numerous cancers including uveal melanoma, melanocytic tumors and mesothelioma, among others. In the present study we report the identificat...

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Detalhes bibliográficos
Publicado no:Cancer Genet
Main Authors: McDonnell, Kevin J., Gallanis, Gregory T., Heller, Kathleen A., Melas, Marilena, Idos, Gregory E., Culver, Julie O., Martin, Sue-Ellen, Peng, David H., Gruber, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447287/
https://ncbi.nlm.nih.gov/pubmed/26774355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2015.12.007
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