A synonymous germline variant in a gene encoding a cell adhesion molecule is associated with cutaneous mast cell tumour development in Labrador and Golden Retrievers

Mast cell tumours are the most common type of skin cancer in dogs, representing a significant concern in canine health. The molecular pathogenesis is largely unknown, but breed-predisposition for mast cell tumour development suggests the involvement of inherited genetic risk factors in some breeds....

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Biasoli, Deborah, Compston-Garnett, Lara, Ricketts, Sally L., Birand, Zeynep, Courtay-Cahen, Celine, Fineberg, Elena, Arendt, Maja, Boerkamp, Kim, Melin, Malin, Koltookian, Michele, Murphy, Sue, Rutteman, Gerard, Lindblad-Toh, Kerstin, Starkey, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447235/
https://ncbi.nlm.nih.gov/pubmed/30901340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007967
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