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Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease: Addressing the Barker Hypothesis With Mendelian Randomization

BACKGROUND: Low birthweight has been associated with a higher risk of hypertension, type 2 diabetes mellitus (T2D), and cardiovascular disease. The Barker hypothesis posits that intrauterine growth restriction resulting in lower birthweight is causal for these diseases, but causality is difficult to...

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Detalhes bibliográficos
Publicado no:Circ Cardiovasc Genet
Main Authors: Zanetti, Daniela, Tikkanen, Emmi, Gustafsson, Stefan, Priest, James R., Burgess, Stephen, Ingelsson, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447084/
https://ncbi.nlm.nih.gov/pubmed/29875125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.117.002054
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