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Smart nanodrug with nuclear location sequences in the presence of MMP-2 to overcome biobarriers and drug resistance

A series of physiological barriers have impeded nanoparticle-based drug formulations (NDFs) from reaching their targeted sites and achieving therapeutic outcomes. In this study, we develop size-controllable stealth doxorubicin-loaded nanodrug coated with CD47 peptides (DOX/sNDF-CD47) based on supram...

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Dades bibliogràfiques
Publicat a:Chemistry
Autors principals: Mo, Liuting, Zhao, Zilong, Hu, Xiaoxiao, Yu, Xuan, Peng, Yongbo, Liu, Hui, Xiong, Mengyi, Fu, Ting, Jiang, Ying, Zhang, Xiaobing, Tan, Weihong
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6447044/
https://ncbi.nlm.nih.gov/pubmed/30681205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201805107
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