Epicardial Injection of Nanoformulated Calcium into Cardiac Ganglionic Plexi Suppresses Autonomic Nerve Activity and Postoperative Atrial Fibrillation: Nanomedicine Therapy for Post-Op Atrial Fibrillation

BACKGROUND: Imbalanced activation of the cardiac autonomic nervous system (CANS) triggers postoperative atrial fibrillation (POAF). Neuronal calcium overload induces apoptosis. We hypothesize that epicardial injection of timed-release nanoformulated-CaCl(2) (nCaCl(2)) into LA ganglionic plexi (GP) m...

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發表在:Heart Rhythm
Main Authors: O’Quinn, Michael P., Dormer, Kenneth J., Huizar, Jose F., Nguyen, Kytai T., Kaszala, Karoly, Sima, Adam, Ellenbogen, Kenneth, Tan, Alex Y.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446939/
https://ncbi.nlm.nih.gov/pubmed/30929671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2018.10.014
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