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Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction
Microglia play a pivotal role in the coordination of brain development and have emerged as a critical determinant in the progression of neurodegenerative diseases; however, the role of microglia in the onset and progression of neurodevelopmental disorders is less clear. Here we show that conditional...
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| Publicat a: | J Exp Med |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Rockefeller University Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446869/ https://ncbi.nlm.nih.gov/pubmed/30846482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181290 |
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