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An amphipathic helix enables septins to sense micrometer-scale membrane curvature
Cell shape is well described by membrane curvature. Septins are filament-forming, GTP-binding proteins that assemble on positive, micrometer-scale curvatures. Here, we examine the molecular basis of curvature sensing by septins. We show that differences in affinity and the number of binding sites dr...
Enregistré dans:
| Publié dans: | J Cell Biol |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Rockefeller University Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446858/ https://ncbi.nlm.nih.gov/pubmed/30659102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807211 |
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