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PLK1 plays dual roles in centralspindlin regulation during cytokinesis
Cytokinesis begins upon anaphase onset. An early step involves local activation of the small GTPase RhoA, which triggers assembly of an actomyosin-based contractile ring at the equatorial cortex. Here, we delineated the contributions of PLK1 and Aurora B to RhoA activation and cytokinesis initiation...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Rockefeller University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446842/ https://ncbi.nlm.nih.gov/pubmed/30728176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201805036 |
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