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TGIF transcription factors repress acetyl CoA metabolic gene expression and promote intestinal tumor growth
Tgif1 (thymine–guanine-interacting factor 1) and Tgif2 repress gene expression by binding directly to DNA or interacting with transforming growth factor (TGF) β-responsive SMADs. Tgifs are essential for embryogenesis and may function in tumor progression. By analyzing both gain and loss of Tgif func...
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| Pubblicato in: | Genes Dev |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6446543/ https://ncbi.nlm.nih.gov/pubmed/30808659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.320127.118 |
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