Antinociceptive activity of petroleum ether fraction obtained from methanolic extract of Clinacanthus nutans leaves involves the activation of opioid receptors and NO-mediated/cGMP-independent pathway

BACKGROUND: Methanol extract (MECN) of Clinacanthus nutans Lindau leaves (family Acanthaceae) demonstrated peripherally and centrally mediated antinociceptive activity via the modulation of opioid/NO-mediated, but cGMP-independent pathway. In the present study, MECN was sequentially partitioned to o...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Main Authors: Zakaria, Zainul Amiruddin, Abdul Rahim, Mohammad Hafiz, Mohd Sani, Mohd Hijaz, Omar, Maizatul Hasyima, Ching, Siew Mooi, Abdul Kadir, Arifah, Ahmed, Qamar Uddin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446312/
https://ncbi.nlm.nih.gov/pubmed/30940120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-019-2486-8
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