Evaluation of therapeutic effects of FAK inhibition in murine models of atherosclerosis

OBJECTIVE: Therapeutic effects of focal adhesion kinase (FAK) inhibition using a small molecule inhibitor was evaluated in apolipoprotein E (apoE) knockout (KO) and low-density lipoprotein receptor (LDLr) KO mouse atherosclerosis models. RESULTS: The prevention trial consisted of an 8-week treatment...

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Bibliografiske detaljer
Udgivet i:BMC Res Notes
Main Authors: Yamaura, Takeshi, Kasaoka, Tatsuhiko, Iijima, Naoko, Kimura, Masaaki, Hatakeyama, Shinji
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Note
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446301/
https://ncbi.nlm.nih.gov/pubmed/30940182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-019-4220-5
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