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4-O-Carboxymethylascochlorin Inhibits Expression Levels of on Inflammation-Related Cytokines and Matrix Metalloproteinase-9 Through NF–κB/MAPK/TLR4 Signaling Pathway in LPS-Activated RAW264.7 Cells

Toll-like receptor 4 (TLR4) and matrix metalloproteinase-9 (MMP-9) are known to play important roles in inflammatory diseases such as arteriosclerosis and plaque instability. The purpose of this study was to perform the effect of 4-O-carboxymethylascochlorin (AS-6) on MMP-9 expression in lipopolysac...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Park, Junyoung, Ha, Sun-Hyung, Abekura, Fukushi, Lim, Hakseong, Magae, Juni, Ha, Ki-Tae, Chung, Tae-Wook, Chang, Young-Chae, Lee, Young-Choon, Chung, Eunyong, Ku, Jiyeon, Kim, Cheorl-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445864/
https://ncbi.nlm.nih.gov/pubmed/31001118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00304
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