Complement-mediated Damage to the Glycocalyx Plays a Role in Renal Ischemia-reperfusion Injury in Mice

BACKGROUND: Complement activation plays an important role in the pathogenesis of renal ischemia-reperfusion (IR) injury (IRI), but whether this involves damage to the vasculoprotective endothelial glycocalyx is not clear. We investigated the impact of complement activation on glycocalyx integrity an...

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Publicado en:Transplant Direct
Autores principales: Bongoni, Anjan K., Lu, Bo, McRae, Jennifer L., Salvaris, Evelyn J., Toonen, Erik J. M., Vikstrom, Ingela, Baz Morelli, Adriana, Pearse, Martin J., Cowan, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Basic Science
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445655/
https://ncbi.nlm.nih.gov/pubmed/30993186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000881
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