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A rare exonic NRXN3 deletion segregating with neurodevelopmental and neuropsychiatric conditions in a three-generation Chinese family

Members of the neurexin gene family, neurexin 1 (NRXN1), neurexin 2 (NRXN2), and neurexin 3 (NRXN3) encode important components of synaptic function implicated in autism and other neurodevelopmental/neuropsychiatric disorders. Loss of function variants have been reported predominantly in NRXN1, with...

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Detalhes bibliográficos
Publicado no:Am J Med Genet B Neuropsychiatr Genet
Main Authors: Yuan, Haiming, Wang, Qingming, Liu, Yanhui, Yang, Wei, He, Yi, Gusella, James F., Song, Jiage, Shen, Yiping
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445570/
https://ncbi.nlm.nih.gov/pubmed/30076746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.32673
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