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Autoantibodies to N-terminally truncated GAD improve clinical phenotyping of individuals with adult-onset diabetes: Action LADA 12

AIMS/HYPOTHESIS: Adult-onset type 1 diabetes, in which the 65 kDa isoform of GAD (GAD65) is a major autoantigen, has a broad clinical phenotype encompassing variable need for insulin therapy. This study aimed to evaluate whether autoantibodies against N-terminally truncated GAD65 more closely define...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Achenbach, Peter, Hawa, Mohammed I., Krause, Stephanie, Lampasona, Vito, Jerram, Samuel T., Williams, Alistair J. K., Bonifacio, Ezio, Ziegler, Anette G., Leslie, R. David
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445455/
https://ncbi.nlm.nih.gov/pubmed/29619531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4605-3
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