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Regulatory mechanisms of fluvastatin and lovastatin for the p21 induction in human cervical cancer HeLa cells

p21, an inhibitor of cyclin-dependent kinase, functions as an oncogene or tumor suppressor depending on the context of a variety of extracellular and intracellular signals. The expression of p21 could be regulated at the transcriptional and/or post-translational levels. The p21 gene is well-known to...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Lin, Chi-Kang, Liu, Shu-Ting, Chang, Cheng-Chang, Huang, Shih-Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445431/
https://ncbi.nlm.nih.gov/pubmed/30939155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214408
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