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A strategy for early detection of response to chemotherapy drugs based on treatment-related changes in the metabolome

We describe a biomarker-based approach to delivering chemotherapy that entails monitoring treatment changes in the circulating metabolome that reflect efficacy. In-vitro, multiple tumor cell lines were exposed to numerous chemotherapeutics. Supernatants were collected at baseline and 72 hours post t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Amin, Shahil, Rattner, Jodi, Keramati, Mohammad Reza, Farshidfar, Farshad, McNamara, Mairéad G., Knox, Jennifer J., Kopciuk, Karen, Vogel, Hans J., Bathe, Oliver F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445409/
https://ncbi.nlm.nih.gov/pubmed/30939138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213942
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