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Multiscale Methods in Drug Design Bridge Chemical and Biological Complexity in the Search for Cures

Drug action is inherently multiscale: it connects molecular interactions to emergent properties at cellular and larger scales. Simulation techniques at each of these different scales are already central to drug design and development, but methods capable of connecting across these scales will extend...

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Vydáno v:Nat Rev Chem
Hlavní autoři: Amaro, Rommie E., Mulholland, Adrian J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445369/
https://ncbi.nlm.nih.gov/pubmed/30949587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41570-018-0148
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