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The lncRNA Neat1 promotes activation of inflammasomes in macrophages

The inflammasome has an essential function in innate immune, responding to a wide variety of stimuli. Here we show that the lncRNA Neat1 promotes the activation of several inflammasomes. Neat1 associates with the NLRP3, NLRC4, and AIM2 inflammasomes in mouse macrophages to enhance their assembly and...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Zhang, Pengfei, Cao, Limian, Zhou, Rongbin, Yang, Xiaolu, Wu, Mian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445148/
https://ncbi.nlm.nih.gov/pubmed/30940803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09482-6
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