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The lncRNA Neat1 promotes activation of inflammasomes in macrophages
The inflammasome has an essential function in innate immune, responding to a wide variety of stimuli. Here we show that the lncRNA Neat1 promotes the activation of several inflammasomes. Neat1 associates with the NLRP3, NLRC4, and AIM2 inflammasomes in mouse macrophages to enhance their assembly and...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6445148/ https://ncbi.nlm.nih.gov/pubmed/30940803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09482-6 |
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