Gliclazide Prevents 5-FU-Induced Oral Mucositis by Reducing Oxidative Stress, Inflammation, and P-Selectin Adhesion Molecules

Oral mucositis (OM) is one of the main side effects of the head and neck cancer treatment, particularly radiotherapy and/or chemotherapy. OM is characterized by ulcers, erythema, dysphagia, xerostomia, and increased susceptibility to opportunistic infections. In the perspective of finding pharmacolo...

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Vydáno v:Front Physiol
Hlavní autoři: Mafra, Cristiane Assunção da Costa Cunha, Vasconcelos, Roseane Carvalho, de Medeiros, Caroline Addison Carvalho Xavier, Leitão, Renata Ferreira de Carvalho, Brito, Gerly Anne de Castro, Costa, Deiziane Viana da Silva, Guerra, Gerlane Coelho Bernardo, de Araújo, Raimundo Fernandes, Medeiros, Aldo Cunha, de Araújo, Aurigena Antunes
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6445135/
https://ncbi.nlm.nih.gov/pubmed/30971955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00327
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