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Exploiting biased reptation for continuous flow preparative DNA fractionation in a versatile microfluidic platform

A new approach is presented for preparative, continuous flow fractionation of sub-10-kbp DNA fragments, which exploits the variation in the field-dependent mobility of the DNA molecules based on their length. Orthogonally pulsed electric fields of significantly different magnitudes are applied to a...

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Detalhes bibliográficos
Publicado no:Microsyst Nanoeng
Main Authors: Gumuscu, Burcu, Bomer, Johan G., de Boer, Hans L., van den Berg, Albert, Eijkel, Jan C. T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444976/
https://ncbi.nlm.nih.gov/pubmed/31057856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/micronano.2017.1
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