hnRNPM induces translation switch under hypoxia to promote colon cancer development

BACKGROUND: Hypoxia suppresses global protein production, yet certain essential proteins are translated through alternative pathways to survive under hypoxic stress. Translation via the internal ribosome entry site (IRES) is a means to produce proteins under stress conditions such as hypoxia; howeve...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Chen, Tsung-Ming, Lai, Ming-Chih, Li, Yi-Han, Chan, Ya-Ling, Wu, Chih-Hao, Wang, Yu-Ming, Chien, Chun-Wei, Huang, San-Yuan, Sun, H. Sunny, Tsai, Shaw-Jenq
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
Soggetti:
Research paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444133/
https://ncbi.nlm.nih.gov/pubmed/30852162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.02.059
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