Protective Effects of Magnesium Glycyrrhizinate on Methotrexate-Induced Hepatotoxicity and Intestinal Toxicity May Be by Reducing COX-2

Magnesium isoglycyrrhizinate (MgIG), which has been widely employed to treat chronic hepatitis, is synthesized from 18-β glycyrrhizic acid, a main component of traditional Chinese medicine Glycyrrhiza uralensis Fisch. Although the protective effects of MgIG on methotrexate (MTX)-induced liver toxici...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Cao, Yuzhu, Shi, Hang, Sun, Zhiguang, Wu, Jiawei, Xia, Yawen, Wang, Yufei, Wu, Yuanyuan, Li, Xiaoman, Chen, Wenxing, Wang, Aiyun, Lu, Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6444054/
https://ncbi.nlm.nih.gov/pubmed/30971913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00119
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