A novel optical tracer for VMAT2 applied to live cell measurements of vesicle maturation in cultured human β-cells

The islet β-cells integrate external signals to modulate insulin secretion to better regulate blood glucose levels during periods of changing metabolic demand. The vesicular monoamine transporter type 2 (VMAT2), an important regulator of CNS neurotransmission, has an analogous role in the endocrine...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Pecic, Stevan, Milosavic, Nenad, Rayat, Gina, Maffei, Antonella, Harris, Paul E.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443945/
https://ncbi.nlm.nih.gov/pubmed/30932004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41891-x
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