Virtual Screen for Repurposing of Drugs for Candidate Influenza a M2 Ion-Channel Inhibitors

Influenza A virus (IAV) matrix protein 2 (M2), an ion channel, is crucial for virus infection, and therefore, an important anti-influenza drug target. Adamantanes, also known as M2 channel blockers, are one of the two classes of Food and Drug Administration-approved anti-influenza drugs, although th...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Radosevic, Draginja, Sencanski, Milan, Perovic, Vladimir, Veljkovic, Nevena, Prljic, Jelena, Veljkovic, Veljko, Mantlo, Emily, Bukreyeva, Natalya, Paessler, Slobodan, Glisic, Sanja
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Cellular and Infection Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443897/
https://ncbi.nlm.nih.gov/pubmed/30972303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00067
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