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Early Dyskinesias in Parkinson’s Disease Patients With Parkin Mutation: A Primary Corticostriatal Synaptopathy?

Mutations in the PARKIN gene cause early-onset Parkinson’s disease (PD). Despite the high proportion of still missing phenotyping data in the literature devoted to early-onset PD, studies suggest that, as compared with late-onset PD, PARKIN patients show dystonia at onset and extremely dose-sensitiv...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Sassone, Jenny, Valtorta, Flavia, Ciammola, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443894/
https://ncbi.nlm.nih.gov/pubmed/30971883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00273
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