Hypermethylation of the G protein‐coupled receptor kinase 6 (GRK6) promoter inhibits binding of C/EBPα, and GRK6 knockdown promotes cell migration and invasion in lung adenocarcinoma cells

We previously reported that the expression of G protein‐coupled receptor kinase 6 (GRK6) is significantly downregulated in lung adenocarcinoma (LADC) tissues, and low expression levels of GRK6 are correlated with poor survival prognosis. However, the specific regulatory mechanisms and functions of G...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Yao, Sumei, Wu, Dandan, Chen, Jinliang, Wang, Peng, Lv, Xuedong, Huang, Jianan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443861/
https://ncbi.nlm.nih.gov/pubmed/30984536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12606
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