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Prevention of mitochondrial genomic instability in yeast by the mitochondrial recombinase Mhr1

Mitochondrial (mt) DNA encodes factors essential for cellular respiration, therefore its level and integrity are crucial. ABF2 encodes a mitochondrial DNA-binding protein and its null mutation (Δabf2) induces mtDNA instability in Saccharomyces cerevisiae. Mhr1 is a mitochondrial recombinase that med...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ling, Feng, Bradshaw, Elliot, Yoshida, Minoru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443803/
https://ncbi.nlm.nih.gov/pubmed/30931958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41699-9
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