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Natural killer cells limit the clearance of senescent lung adenocarcinoma cells

Senescence is an important p53-controlled tumor suppressor program that not only opposes the proliferation of cancer cells but also promotes their immune-mediated clearance in certain contexts. In hepatocellular cancer, p53 induction promotes an innate immune cell-mediated clearance of senescent cel...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Stokes, Kate L., Cortez-Retamozo, Virna, Acosta, Jonuelle, Lauderback, Brian, Robles-Oteiza, Camila, Cicchini, Michelle, Pittet, Mikael J., Feldser, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443683/
https://ncbi.nlm.nih.gov/pubmed/30936429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0133-3
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