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The LRRC8-mediated volume-regulated anion channel is altered in glaucoma

Regulation of cellular volume is an essential process to balance volume changes during cell proliferation and migration or when intracellular osmolality increases due to transepithelial transport. We previously characterized the key role of volume-regulated anion channels (VRAC) in the modulation of...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Gasull, Xavier, Castany, Marta, Castellanos, Aida, Rezola, Mikel, Andrés-Bilbé, Alba, Canut, Maria Isabel, Estévez, Raúl, Borrás, Teresa, Comes, Núria
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443673/
https://ncbi.nlm.nih.gov/pubmed/30931966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41524-3
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