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T helper 2 differentiation is necessary for development of lymphedema
T cells infiltrating lymphedematous tissues have a mixed T helper 1 (Th1) and Th2 differentiation profile. Treatment with neutralizing antibodies targeting cytokines that promote Th2 differentiation [interleukin 4 (IL-4) and IL-13] decreases the severity of lymphedema in preclinical models, suggesti...
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| Udgivet i: | Transl Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443462/ https://ncbi.nlm.nih.gov/pubmed/30633890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2018.12.003 |
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