Hydrogen sulfide inhibits PCSK9 expression through the PI3K/Akt-SREBP-2 signaling pathway to influence lipid metabolism in HepG2 cells

Hydrogen sulfide (H(2)S) is an endogenous gaseous signaling molecule that plays important roles in the cardiovascular system. In our previous studies, we demonstrated that H(2)S regulates lipid metabolism. In the present study, we aimed to explore the mechanisms through which H(2) regulates lipid me...

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Udgivet i:Int J Mol Med
Main Authors: Xiao, Jun, Bai, Xue-Qin, Liao, Ling, Zhou, Min, Peng, Juan, Xiang, Qiong, Ren, Zhong, Wen, Hong-Yan, Jiang, Zhi-Sheng, Tang, Zhi-Han, Wang, Mei-Mei, Liu, Lu-Shan
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443339/
https://ncbi.nlm.nih.gov/pubmed/30864739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4118
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