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Endothelial dysfunction induces atherosclerosis: increased aggrecan expression promotes apoptosis in vascular smooth muscle cells

Endothelial dysfunction-induced lipid retention is an early feature of atherosclerotic lesion formation. Apoptosis of vascular smooth muscle cells (VSMCs) is one of the major modulating factors of atherogenesis, which accelerates atherosclerosis progression by causing plaque destabilization and rupt...

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Pubblicato in:BMB Rep
Autori principali: Kim, Sang-Min, Huh, Jae-Wan, Kim, Eun-Young, Shin, Min-Kyung, Park, Ji-Eun, Kim, Seong Who, Lee, Wooseong, Choi, Bongkun, Chang, Eun-Ju
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443320/
https://ncbi.nlm.nih.gov/pubmed/30638179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2019.52.2.282
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