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Frozen‐hydrated chromatin from metaphase chromosomes has an interdigitated multilayer structure

Cryo‐electron tomography and small‐angle X‐ray scattering were used to investigate the chromatin folding in metaphase chromosomes. The tomographic 3D reconstructions show that frozen‐hydrated chromatin emanated from chromosomes is planar and forms multilayered plates. The layer thickness was measure...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Chicano, Andrea, Crosas, Eva, Otón, Joaquín, Melero, Roberto, Engel, Benjamin D, Daban, Joan‐Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443200/
https://ncbi.nlm.nih.gov/pubmed/30609992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899769
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