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Transposable elements drive widespread expression of oncogenes in human cancers
Transposable elements (TEs) are an abundant and rich genetic resource of regulatory sequences(1–3). Cryptic regulatory elements within TEs can be epigenetically reactivated in cancer to influence oncogenesis in a process termed onco-exaptation(4). However, the prevalence and impact of TE onco-exapta...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6443099/ https://ncbi.nlm.nih.gov/pubmed/30926969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0373-3 |
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