PD-L1 upregulation in myeloma cells by panobinostat in combination with interferon-γ

Immunotherapy is revolutionizing the treatment paradigm for multiple myeloma (MM). Interferon (IFN)-γ is essential for immune responses, whereas immune checkpoint molecules, such as programmed cell death-1 ligand-1 (PD-L1), mitigate the beneficial anti-tumor immune responses. As HDAC inhibitors alte...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Iwasa, Masami, Harada, Takeshi, Oda, Asuka, Bat-Erdene, Ariunzaya, Teramachi, Jumpei, Tenshin, Hirofumi, Ashtar, Mohannad, Oura, Masahiro, Sogabe, Kimiko, Udaka, Kengo, Fujii, Shiro, Nakamura, Shingen, Miki, Hirokazu, Kagawa, Kumiko, Ozaki, Shuji, Abe, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6443002/
https://ncbi.nlm.nih.gov/pubmed/30956773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26726
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