Blastic plasmacytoid dendritic cell neoplasm: genomics mark epigenetic dysregulation as a primary therapeutic target

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy for which there is still no effective therapy. In order to identify genetic alterations useful for a new treatment design, we used whole-exome sequencing to analyze 14 BPDCN patients and the patient-...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Sapienza, Maria Rosaria, Abate, Francesco, Melle, Federica, Orecchioni, Stefania, Fuligni, Fabio, Etebari, Maryam, Tabanelli, Valentina, Laginestra, Maria Antonella, Pileri, Alessandro, Motta, Giovanna, Rossi, Maura, Agostinelli, Claudio, Sabattini, Elena, Pimpinelli, Nicola, Truni, Mauro, Falini, Brunangelo, Cerroni, Lorenzo, Talarico, Giovanna, Piccioni, Rossana, Amente, Stefano, Indio, Valentina, Tarantino, Giuseppe, Brundu, Francesco, Paulli, Marco, Berti, Emilio, Facchetti, Fabio, Dellino, Gaetano Ivan, Bertolini, Francesco, Tripodo, Claudio, Rabadan, Raul, Pileri, Stefano A.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442957/
https://ncbi.nlm.nih.gov/pubmed/30381297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.202093
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