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Design and Sample Size Considerations for Alzheimer’s Disease Prevention Trials Using Multistate Models
BACKGROUND/AIMS: Clinical trials for Alzheimer’s disease (AD) have been aimed primarily at persons who have cognitive symptoms at enrollment. However, researchers are now recognizing that the pathophysiological process of AD begins years if not decades prior to the onset of clinical symptoms. Succes...
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| Vydáno v: | Clin Trials |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6442939/ https://ncbi.nlm.nih.gov/pubmed/30922116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774518816323 |
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