Taurine transporter (TauT) deficiency impairs ammonia detoxification in mouse liver

Hepatic ammonia handling was analyzed in taurine transporter (TauT) KO mice. Surprisingly, hyperammonemia was present at an age of 3 and 12 months despite normal tissue integrity. This was accompanied by cerebral RNA oxidation. As shown in liver perfusion experiments, glutamine production from ammon...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Qvartskhava, Natalia, Jin, Cheng Jun, Buschmann, Tobias, Albrecht, Ute, Bode, Johannes Georg, Monhasery, Niloufar, Oenarto, Jessica, Bidmon, Hans Jürgen, Görg, Boris, Häussinger, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442586/
https://ncbi.nlm.nih.gov/pubmed/30862735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813100116
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados