Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB)

BACKGROUND: Breast cancer (BC) is one of the most common malignant tumors in women around the world. Atorvastatin (ATO) was found to be associated with a decreased risk of recurrence and mortality in cancer. But the exact mechanism of its carcinostatic effects is unclear. The expression level of Ras...

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Pubblicato in:Biomed Res Int
Autori principali: Ma, Qing, Gao, Yang, Xu, Pei, Li, Kai, Xu, Xiaolong, Gao, Jingbo, Qi, Yuwen, Xu, Jingjing, Yang, Yan, Song, Wenjing, He, Xin, Liu, Shuting, Yuan, Xiaoning, Yin, Weinan, He, Yanqi, Pan, Wenting, Wei, Lei, Zhang, Jingwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442491/
https://ncbi.nlm.nih.gov/pubmed/31011573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3235021
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