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Inhibition of Tau Aggregation by Three Aspergillus nidulans Secondary Metabolites: 2,ω-dihydroxyemodin, asperthecin and asperbenzaldehyde

The aggregation of the microtubule-associated protein tau is a significant event in many neurodegenerative diseases including Alzheimer’s disease. The inhibition or reversal of tau aggregation is therefore a potential therapeutic strategy for these diseases. Fungal natural products have proven to be...

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Detalhes bibliográficos
Publicado no:Planta Med
Main Authors: Paranjape, Smita R., Chiang, Yi-Ming, Sanchez, James F., Entwistle, Ruth, Wang, Clay C. C., Oakley, Berl R., Gamblin, T. Chris
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442474/
https://ncbi.nlm.nih.gov/pubmed/24414310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0033-1360180
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