Diurnal Rhythms Spatially and Temporally Organize Autophagy

Circadian rhythms are a hallmark of physiology, but how such daily rhythms organize cellular catabolism is poorly understood. Here, we used proteomics to map daily oscillations in autophagic flux in mouse liver and related these rhythms to proteasome activity. We also explored how systemic inflammat...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ryzhikov, Mikhail, Ehlers, Anna, Steinberg, Deborah, Xie, Wenfang, Oberlander, Eitan, Brown, Samuel, Gilmore, Petra E., Townsend, Reid R., Lane, William S., Dolinay, Tamas, Nakahira, Kiichi, Choi, Augustine M.K., Haspel, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6442472/
https://ncbi.nlm.nih.gov/pubmed/30759397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.01.072
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